Improving Hormone Evaluation: iollo's Innovative Testing for Targeted Hormone Balancing Strategies

March 15, 2024


Hormonal balance is a critical aspect of overall well-being, and its optimization can significantly improve patients' quality of life. iollo's advanced metabolomic testing offers healthcare providers a powerful tool to identify hormonal imbalances and develop personalized interventions for their patients. 

This educational material aims to familiarize physicians with the key hormonal health markers measured by iollo's test, their interpretation, and the potential benefits for patients experiencing various hormone-related health issues.

Who May Benefit from This Test?

iollo's hormonal health testing can be particularly beneficial for patients experiencing various symptoms or conditions related to hormonal imbalances. Some of the key indications for testing include:

  • Fatigue or low energy: Patients with persistent fatigue or low energy levels may have underlying hormonal imbalances, such as adrenal dysfunction or thyroid disorders, contributing to their symptoms.
  • Mood swings or irritability: Individuals experiencing frequent mood swings, irritability, or anxiety may have hormonal imbalances affecting their emotional well-being, such as fluctuations in estrogen or progesterone levels.
  • Difficulty sleeping or insomnia: Sleep disturbances or chronic insomnia may be related to hormonal imbalances, particularly in cortisol or melatonin levels, which regulate the sleep-wake cycle.
  • Polycystic ovary syndrome (PCOS): Women with PCOS often experience hormonal imbalances, such as elevated androgens and insulin resistance, which can lead to various symptoms, including irregular menstrual cycles, acne, and weight gain.
  • Menopause or andropause symptoms: Patients experiencing symptoms related to menopause (in women) or andropause (in men), such as hot flashes, night sweats, or decreased libido, may benefit from hormonal testing to identify specific imbalances and guide targeted interventions.

Other patients who may benefit from hormonal health testing include those with a history of hormonal disorders, individuals with unexplained infertility, and those with chronic stress or adrenal fatigue symptoms.

Understanding Hormonal Health Markers

iollo's Hormonal Health Panel measures a comprehensive set of biomarkers that provide insights into various aspects of hormonal function. Some of the key markers include:

  1. Cortisol
  • Cortisol is a glucocorticoid hormone produced by the adrenal glands in response to stress and is involved in regulating energy metabolism, immune function, and blood pressure.
  • High levels of cortisol may indicate chronic stress or adrenal dysfunction [1].
  1. Dehydroepiandrosterone Sulfate (DHEAS)
  • DHEAS is a precursor for sex hormones, such as estrogen and testosterone, and is produced by the adrenal glands [2].
  • Low levels of DHEAS have been associated with adrenal insufficiency, while high levels may indicate conditions such as polycystic ovary syndrome (PCOS) or congenital adrenal hyperplasia [3].

Interpreting Results and Patient Benefits

iollo's metabolomic testing provides valuable insights into patients' hormonal health status:

  • Identifying imbalances in key hormonal markers can reveal underlying issues such as adrenal dysfunction, sex hormone imbalances, or thyroid disorders.
  • Patients struggling with hormone-related health issues, such as fatigue, mood swings, sleep disturbances, PCOS, or menopause/andropause symptoms, can particularly benefit from the comprehensive analysis of their metabolomic profile.

iollo's test results are highly actionable, offering personalized recommendations based on each patient's unique health history and context:

  • For example, patients with elevated cortisol levels may benefit from stress-reduction techniques, such as mindfulness, meditation, or yoga.

Physicians can assist patients in prioritizing 2-3 key recommendations to focus on initially, based on the most significant hormonal imbalances and the patient's individual goals and preferences. Regular monitoring of these biomarkers can also help track patients' progress and optimize their treatment plans over time.


iollo's advanced metabolomic testing provides healthcare providers with a powerful tool to assess and optimize their patients' hormonal health. By understanding the key markers measured and their implications for hormonal function, physicians can develop personalized interventions that address underlying imbalances and support their patients' well-being. Integrating Iollo's testing into clinical practice can complement other functional and integrative approaches to hormonal health and vitality, ultimately helping patients achieve optimal health outcomes.

To learn more about iollo's metabolomic testing and how it can benefit your patients, please visit or contact our support team at


[1] Sturmhöfel and Bartke. (1998). Alcohol health and research world 22.3: 153.
[2] Sahu et al. (2020). Steroids 153: 108507.

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iollo is for anyone who wants to be empowered with information and data about their blood metabolome. iollo tests are intended exclusively for wellness purposes. iollo cannot provide you with medical advice or diagnose you with any disease or condition. Any information provided by iollo is not medical advice and is not intended to replace the advice of your medical professional.